By W.W. de Herder, D. O'Toole, G. Rindi, B. Wiedenmann
This 'Neuroendocrinology' unique factor presents a suite of papers generated on the first consensus convention dedicated to gastrointestinal neuroendocrine tumors. The convention was once held in Frascati (Rome, Italy) in November 2005. the focal point used to be on neuroendocrine tumors of foregut starting place, abdominal, duodenum and pancreas. a typical technique in accordance with WHO tumors type used to be followed with sixty three specialists and working towards clinicians confronting their event and evidence-based information to plot powerful concepts for the administration of sufferers with this ignored melanoma affliction. Papers are equipped on an anatomical foundation, particular matters are mentioned and minimum consensus statements outlined and highlighted for simple attractiveness. This booklet comprises subject matters akin to: type and Epidemiology; scientific presentation/Prognosis/Heredity; Diagnostic tactics (imaging-lab tests); Pathology and Genetics; Surgical treatment (curative and palliative); Loco-Regional Ablative treatment; Liver Transplantation; scientific treatment (biotherapy and chemotherapy); Peptide Receptor Radionuclide remedy and Follow-Up scheduling. Readers should be capable of finding particular solutions to key questions for particular tumors, reminiscent of the follow-up for belly variety 1 carcinoids; the diagnostic strategy for gastrinoma or the set of rules for liver metastasis remedy in sufferers with pancreatic non-functioning neuroendocrine carcinomas.
Read or Download Enets Consensus Guidelines for the Management of Patients With Digestive Neuroendocrine Tumors: Part 1 - Stomach, Duodenum and Pancreas PDF
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Extra info for Enets Consensus Guidelines for the Management of Patients With Digestive Neuroendocrine Tumors: Part 1 - Stomach, Duodenum and Pancreas
Palliative surgery (to primary or metastases) may also be performed following multidisciplinary discussions and includes palliative or debulking resections (resection of 190% of tumor burden) to control symptoms related to hormonal hypersecretion [10, 14, 17, 33]. Bilateral adrenalectomy should be performed in selected cases with ACTH secretion resulting in Cushing syndrome [38, 39]. Liver transplantation may be indicated for a small number of patients, without extrahepatic metastases , in whom life-threatening hormonal symptoms persist despite maximal medical therapy and where standard surgery is not feasible.
Falchetti, Department of Internal Medicine, University of Florence and Centro di Riferimento Regionale Tumori Endocrini Ereditari, Azienda Ospedaliera Careggi, Florence (Italy); P. Goretzki, Department of Surgery, Städtisches Klinikum Neuss, Lukas Hospital, Neuss (Germany); D. Gross, Department of Endocrinology and Metabolism, Hadassah University, Jerusalem (Israel); D. Hochhauser, Department of Oncology, Royal Free University, London (UK); R. Hyrdel, Department of Internal Medicine, Martin University, Martin (Slovakia); R.
Neth J Med 1989;35:86–94. 33 Cohen MS, Bower RH, Fidler SM, Johnsonbaugh RE, Sode J: Inhibition of insulin release by diphenylhydantoin and diazoxide in a patient with benign insulinoma. Lancet 1973;i:40–41. Neuroendocrinology 2006;84:183–188 187 34 Brodows RG, Campbell RG: Control of refractory fasting hypoglycemia in a patient with suspected insulinoma with diphenylhydantoin. J Clin Endocrinol Metab 1974; 38: 159–162. 35 Lamberts SW, van der Lely AJ, de Herder WW, Hofland LJ: Octreotide. N Engl J Med 1996;334:246–254.
Enets Consensus Guidelines for the Management of Patients With Digestive Neuroendocrine Tumors: Part 1 - Stomach, Duodenum and Pancreas by W.W. de Herder, D. O'Toole, G. Rindi, B. Wiedenmann