By Oppenheim J.J., Howard O.M.Z., Goetzl E.
This introductory evaluate serves to introduce the reader to numerous households of mobile chemoattractants together with cytokines referred to as chemokines, as neuropeptides, parts of the supplement cascade, and cyclooxygenase pathways. those ligands percentage the ability to make use of seven transmembrane (STM) G protein-coupled receptors. As is right of alternative cyto-kines, those ligands are multifunctional and, as well as mobilizing inflammatory cells to websites of an infection and harm, act on a large spectrum of progenitor cells and on nonleukocytes. hence, a few of these ligands perform fetal improvement, others on hematopoiesis on trafficking and homing of cells to tissues and organs, at the induction of inflammatory and immune responses, and on regulating cellphone adhesion and angiogenesis. we are going to additionally assessment experiences that quite a few viruses and microorganisms have tailored and discovered to avoid those mediators of host safeguard by means of generating agonists or antagonists or, as illustrated by means of HIV-1, through the use of chemokine receptors as access websites for mobile invasion.
Read Online or Download Chemotactic Factors, Neuropeptides, and Other Ligands for Seven Transmembrane Receptors PDF
Best chemistry books
For the 1st time the self-discipline of recent inorganic chemistry has been systematized in keeping with a plan developed through a council of editorial advisors and specialists, between them 3 Nobel laureates (E. O. Fischer, H. Taube and G. Wilkinson). instead of generating a suite of unrelated assessment articles, the sequence creates a framework which displays the inventive power of this medical self-discipline.
- Chemistry and Functions of Colicins
- Geoquimica recreativa
- Chemie: Grundlagen, Aufbauwissen, Anwendungen und Experimente, 8. Auflage
- Physikalische Chemie: Eine Einfuhrung nach neuem Konzept mit zahlreichen Experimenten
- Trace Elements- Their Distribution and Effects in the Environment
Additional info for Chemotactic Factors, Neuropeptides, and Other Ligands for Seven Transmembrane Receptors
C. E. (1998). Altered neuroimmunoendocrine communication during a condition of chronically increased brain corticotropin-releasing hormone drive. Ann. NY Acad. Sci. 840, 444±455. Roos, R. , Legler, D. , and Moser, B. (1997). Identification of CCR8, the receptor for the human CC chemokine I-309. J. Biol. Chem. 272, 17251±17254. Rossi, D. , Vicari, A. , McClanahan, T. , and Zlotnik, A. (1997). Identification through bioinformatics of two new macrophage proinflammatory human chemokines. J. Immunol.
Ann. NY Acad. Sci. 496, 217±225. , and Lindgren, J. A. (1994). Leukotrienes and lipoxins - new potential performers in the regulation of human myelopoiesis. Leuk. Res. 18, 727±732. Stenzel-Poore, M. , Duncan, J. , Rittenberg, M. , Bakke, A. , and Heinrichs, S. C. (1995). CRH Overproduction in transgenic mice: behavioral and immune system modulation. Ann. NY Acad. Sci. 780, 36±48. Stringer, S. , and Gallagher, J. T. (1997). Specific binding of the chemokine platelet factor 4 to heparan sulfate. J.
Dahinden, C. , and Baggiolini, M. (1997). Eotaxin-2, a novel CC chemokine that is selective for the chemokine receptor CCR3, and acts like eotaxin on human eosinophil and basophil leukocytes. J. Exp. Med. 185, 2171±2176. , Mattis, A. , and Lipp, M. (1996). A putative chemokine receptor, BLR1, directs B cell migration to defined lymphoid organs and specific anatomic compartments of the spleen. Cell. 87, 1037±1047. Gallin, J. , Goldstein, I. , and Snyderman, R. (1992). '' Raven Press, New York.
Chemotactic Factors, Neuropeptides, and Other Ligands for Seven Transmembrane Receptors by Oppenheim J.J., Howard O.M.Z., Goetzl E.