By Syed Z. Ali MD, Yener S. Erozan MD, Ralph H. Hruban MD
Medical and radiologic examinations can't reliably distinguish benign or inflammatory pancreatic sickness from carcinoma. The elevated use of pancreatic advantageous needle aspiration (FNA) besides advances in imaging thoughts and the creation of endoscopic ultrasound suggestions have ended in much better detection and popularity of pancreatic lots. accordingly, pancreatic cytopathology is fundamental to exact pre-operative analysis, but it's a hard diagnostic sector with various power pitfalls and ???„????look-alike???„???? lesions. Skillful popularity and an understanding of the restrictions of the strategy are crucial in fending off misdiagnosis of those harmful lesions. Atlas of Pancreatic Cytopathology with Histopathologic Correlations fills a void in present pathology literature. With 450 high-resolution photos, together with photographs of histopathologic and radiologic good points, this functional atlas provides an built-in method of diagnostic cytopathology that might support general practitioner cytopathologists, cytotechnologists, and pathologists stay away from capability pitfalls and ""look-alike"" lesions. Written through well-known specialists within the box, the vast high-resolution colour photographs of the attribute gains of pancreatic illness are provided with targeted descriptions that disguise vintage positive factors, diagnostic clues, and strength pitfalls. Atlas of Pancreatic Cytopathology with Histopathologic Correlations is a beneficial source for the professional cytopathologist, basic and surgical pathologists, pathology trainees, and cytotechnologists.
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Extra info for Atlas of Pancreatic Cytopathology with Histopathologic Correlations
This amorphous material should not be confused with thick mucin. 35 — Lymphoepithelial cyst. An intimate admixture of polymorphous lymphocytes and superficial-type squamous epithelial cells and anucleate squames is seen. A bimodal admixture of these two cell types is highly suggestive of lymphoepilthelial cyst. 36 — Lymphoepithelial cyst. Cell block section displays an aggregate of lymphoid tissue and juxtaposed benign squamous epithelium, which forms the lining of the cystic structure. An additional helpful finding, beautifully illustrated here, is an admixture of abundant anucleate squames and blood in the background.
19 — Pseudocyst. The cyst contains necrotic debris and is lined by macrophages and granulation tissue. The epithelium lining cystic neoplasms of the pancreas, such as the mucinous cystic neoplasm, can be focally denuded, mimicking a pseudocyst. Careful attention to the nature of the stroma (ovarian-type in mucinous cystic neoplasms) and adequate sampling can avoid this diagnostic pitfall. (Hematoxylin and eosin stain, medium power). 20 — Pseudocyst. Polymorphous cellular infiltrate with predominantly lymphocytes and histiocytes is seen.
Chapter 2: Radiologic Characteristics of Pancreatic Disease 25 Selected Cases Illustrating Salient Radiologic Characteristics Case 10 Large nonfunctioning pancreatic endocrine neoplasm (47-year-old woman with large pancreatic mass). (A) Arterial phase contrast-enhanced axial CT of the upper abdomen shows a very large mass in the tail of the pancreas (arrows). The tumor has an enhancing rim and a necrotic center. It invades into the splenic hilum and has occluded the splenic vein with multiple varices seen (arrowheads).
Atlas of Pancreatic Cytopathology with Histopathologic Correlations by Syed Z. Ali MD, Yener S. Erozan MD, Ralph H. Hruban MD