Download PDF by Anthony W.H. Chan: Atlas of Liver Pathology

By Anthony W.H. Chan

ISBN-10: 1461491134

ISBN-13: 9781461491132

ISBN-10: 1461491142

ISBN-13: 9781461491149

The liver is a fancy organ because of its designated microscopic constitution, elaborate metabolic features and susceptibility to a wide selection of insults, manifesting in numerous histological styles. Atlas of Liver Pathology considers either adjustments noticeable in clinical liver biopsies in addition to lesional biopsies while the specimen has been taken from a mass. The e-book begins through reviewing basic constitution and its editions and the optimum ways for the coaching of histological sections for diagnostic liver pathology. the next chapters are devoted to developmental, metabolic, infectious, drug comparable, autoimmune, biliary, vascular and neoplastic problems. sections on liver pathology in being pregnant and transplantation finish the paintings. Macroscopic illustrations are incorporated the place acceptable. All photos are complemented via legends describing the image and supplying correct comparable information.

Authored by means of nationally and the world over well-known pathologists, Atlas of Liver Pathology is a priceless source that serves as a short reference advisor for the prognosis of traditional and strange diseases.

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This active form of cell death results from the activation of caspases and endonucleases through two overlapping signalling pathways: the extrinsic death receptor-initiated pathway and the intrinsic mitochondrial pathway. 2 Cellular Damage 25 Fig. 21 Apoptotic body. Here, an apoptotic body is associated with a small group of mononuclear inflammatory cells. Apoptotic bodies are a nonspecific finding occurring in a very wide range of acute and chronic liver diseases, and sometimes may be observed in normal liver.

Congenital hepatic fibrosis is characterised macroscopically by hepatomegaly with multiple nodules separated by thick fibrous bands. Histologically, the entire liver is divided into irregular hepatic nodules with a jigsaw puzzle appearance by diffuse periportal and portal-portal bridging fibrosis, and resembles biliary-type cirrhosis. Fibrous septa contain numerous irregularly dilated ductal structures at the portal–parenchymal interface. The ductal structures are lined by cuboidal or columnar cells and may contain inspissated bile or eosinophilic material.

55 Amyloidosis. Extensive amorphous eosinophilic extracellular deposits are present within the hepatic sinusoids in a linear manner and with compression of the cords of hepatocytes. The presence of amyloid may be confirmed by a Congo red stain (pinkish in light microscopy with apple-green birefringence under polarized light). The liver commonly is involved in systemic amyloidosis. There are three main histologic patterns of amyloid deposition in the liver: vascular (in the wall of blood vessels), sinusoidal (in the sinusoids beneath the space of Disse in either a linear or globular manner), and stromal (in portal tract connective tissue).

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Atlas of Liver Pathology by Anthony W.H. Chan

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