By Pere Gines
There was little or no written at the interplay of the liver and kidney. This e-book addresses the expanding prevalence and value of illnesses, reminiscent of ascites, renal disorder, cirrhosis and high blood pressure the place either organs are concerned. This textbook is vital, even for proven practitioners and comprises present information about therapy and treatment for sufferers with cirrhosis and ascites, truly and successfully provided through the pinnacle foreign specialists inside this box. the second one variation is completely revised and up-to-date and locations larger emphasis on remedy.
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Additional resources for Ascites and Renal Dysfunction in Liver Disease: Pathogenesis, Diagnosis, and Treatment
Analysis of the determinants of renal cortical pCO2. Am J Physiol 1984; 247:F466–F474. 17 Scholz H, Schurek HJ, Eckardt KV et al. Oxygen-dependent erythropoietin production by the isolated perfused kidney. Pflugers Arch 1991; 418:228–33. 18 Alonso-Galicia M, Drummond HA, Reddy KK et al. Inhibition of 20-HETE production contributes to the vascular responses to nitric oxide. Hypertension 1997; 29:320–5. 19 Schnermann J, Wahl M, Liebau G, Fischbach H. Balance between tubular flow rate and net fluid reabsorption in the proximal convolution of the rat kidney.
L-Arginine nitric oxide system NO is derived from the amino acid L-arginine in the presence of the enzyme NOS and various cofactors (149–151). Two major families of NOS isoforms have been described, the constitutive type NOS and the inducible type NOS (iNOS). Endothelial NOS (eNOS) and neuronal NOS Physiology of the Renal Circulation (nNOS) are considered the constitutive NOS, which require intracellular Ca2+ mobilization for activation. Hormonal activation of eNOS stimulates NO production, which is critical to maintain vessel tone.
Prostaglandins Prostaglandins are derived from the metabolism of arachidonic acid (100–102). In the presence of phospholipase A2, arachidonic acid is freed from membrane phospholipids and can be converted to the various prostaglandins in the presence of the enzyme prostaglandin endoperoxide synthase or cyclooxygenase (COX). Two isoforms of COX have been demonstrated: COX-1 and COX-2 (101–103). COX-1 is expressed constitutively in most cells throughout the organism and is responsible for the generation of prostaglandins in response to various hormones.
Ascites and Renal Dysfunction in Liver Disease: Pathogenesis, Diagnosis, and Treatment by Pere Gines